IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination more...
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Volume : 5, Issue : 4, Year : 2020
Article Page : 312-316
Melanoma is an aggressive malignancy, and early diagnosis and treatment can reduce mortality in patients. A new or changing lesion is the most common warning sign of melanoma. In amelanotic tumors, diagnosis may be delayed. Amelanotic melanoma is a form of melanoma in which malignant cells have little or no pigment. Amelanotic melanoma is classically described as skin coloured but a subset of these tumors are red, pink or erythematous. Typical early lesions present as asymmetrical macular lesions. FNAC may show varied cytomorphology ranging from epithelioid to spindled to plasmacytoid pleomorphic cells with
marked anisonucleosis and eosinophilic to basophilic cytoplasm with intranuclear pseudoinclusions and cytoplasmic vacoulations admixed with bi- and multinucleate giant cells.We present a case series of varied presentation of amelanotic melanoma with its cytomorphological features.
Keywords: Amelanotic, Clinical Presentation, Cytomorphology, FNAC, Melanoma.
How to cite : Warsi S , Talha M, Ekram F T, Akhtar K , Amelanotic melanoma: A challenging cytological diagnosis- A case series. IP Arch Cytol Histopathol Res 2020;5(4):312-316
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