IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267


IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination more...

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Case Report

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Kafil Akhtar*, Sumbul Warsi, Fauzia Talat, Mohd Talha

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Spindle cell carcinoma of the parotid- A rare case entity with review of literature

Case Report

Author Details : Kafil Akhtar*, Sumbul Warsi, Fauzia Talat, Mohd Talha

Volume : 5, Issue : 4, Year : 2020

Article Page : 323-326


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Spindle cell carcinoma of the salivary gland is very rare. Spindle cell carcinoma is a variant of squamous cell carcinoma with an aggressive course. We present a rare case of spindle cell carcinoma of the parotid in a 54-year-old male, who presented with a rapidly enlarging mass in the right parotid gland. Histopathologically, the tumour was composed of foci of squamous cell carcinoma with sheets of malignant squamoid cells and spindle cell sarcoma with scattered pleomorphic, plump to spindle- shaped cells with foci of bone formation. Immunohistochemical studies revealed cytokeratin positivity and vimentin negativity in the squamous cell carcinoma component with focal positivity for epithelial membrane antigen and negative expression of cytokeratin and vimentin positivity in the sarcomatoid component. A final diagnosis of primary spindle cell carcinoma of the parotid gland was given. Our patient is alive and well with no clinical or radiological evidence of recurrence or metastatic disease after 12 months of follow up period.

Keywords: Salivary gland, Spindle cell carcinoma, Histopathology, Immunohistochemistry.

How to cite : Akhtar K , Warsi S, Talat F, Talha M, Spindle cell carcinoma of the parotid- A rare case entity with review of literature. IP Arch Cytol Histopathol Res 2020;5(4):323-326

Copyright © 2020 by author(s) and IP Arch Cytol Histopathol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)