IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267


IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination more...

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Radha R Kabbur*, Vidya K, Manasa Reddy K

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Histomorphological study of colonoscopic biopsies in patients presenting with chronic diarrhea

Original Article

Author Details : Radha R Kabbur*, Vidya K, Manasa Reddy K

Volume : 6, Issue : 3, Year : 2021

Article Page : 166-172


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Background: Colonoscopic biopsy is an important tool in the diagnosis of large bowel diseases affected by a wide range of conditions both non neoplastic and neoplastic which can present with chronic diarrhea. The causes for chronic diarrhoea vary depending on socio-economic factors, hygienic practices. Studies exploring the causes of chronic diarrhea in developing countries are few, with no generalized uniformity. With this background information the present study is planned to know various causes of chronic diarrhea by histopathological study.
Aim: To assess the histopathological findings among colonoscopic biopsies in patients undergoing work up for chronic diarrhea and to deternine the sex and age incidence in major causes
Materials and Methods : A total of 100 colonoscopic biopsies from the patients suffering from chronic diarrhea were obtained from the Department of Medical Gastroenterology and received in the Department of Pathology, VIMS & RC Bangalore from January 2014 to January 2015 were studied.
Results: In the present study 100 colonoscopic biopsies were studied with a mean age of 45 years and male to female ratio of 3.3:1. Out of 100 cases, 92 cases were non-neoplastic lesions, 3 cases were benign and 5 cases were malignant lesions. Among 92 cases, majority of them were inflammatory lesions accounting to 85 cases (92.4%), 4 (4.3%) cases were polypoid lesions. The inflammatory bowel disease were more commonly seen in 31-40 years with the male preponderance.
Conclusion: Colonoscopy biopsy is a useful investigation to be carried out in patients with chronic diarrhea for proper diagnosis and treatment. It has a role in diagnosis, follow up and treatment, especially in cases of inflammatory bowel disease and malignancies. It is the gold standard for cancer surveillance.

Keywords: Adenocarcinoma, Colonoscopy Inflammatory bowel disease, Signet ring cell carcinoma

How to cite : Kabbur R R, Vidya K, Manasa Reddy K, Histomorphological study of colonoscopic biopsies in patients presenting with chronic diarrhea. IP Arch Cytol Histopathol Res 2021;6(3):166-172

Copyright © 2021 by author(s) and IP Arch Cytol Histopathol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)

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