IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better more...


Article type

Case Report


Article page

305-310


Authors Details

Ninad R Patil, Manjul Tripathi, Sonikpreet Aulakh, Nirmalya Banerjee, Aravind Sekar, Aman Batish, Chiraj Kamal Ahuja, Sandeep Mohindra*


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Xanthomatous meningioma, a rare histological variant: Case report


Case Report

Author Details : Ninad R Patil, Manjul Tripathi, Sonikpreet Aulakh, Nirmalya Banerjee, Aravind Sekar, Aman Batish, Chiraj Kamal Ahuja, Sandeep Mohindra*

Volume : 6, Issue : 4, Year : 2021

Article Page : 305-310

https://doi.org/10.18231/j.achr.2021.067



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Abstract

Xanthomatous meningioma is a WHO grade I metaplastic meningioma where neoplastic cells contain lipid-filled vacuolated cytoplasm. The origin of xanthomatous meningiomas is believed to be from meningothelial cells but diagnosis remains difficult because of their close resemblance with the histiocytes. Peculiar radiographic features may aid in diagnosis, however, definitive diagnosis requires immunohistochemical staining. We report a case of 43-year-old male with sphenoid wing meningioma revealing xanthomatous changes and received treatment as grade 1 meningioma. Though the exact pathophysiology remains unknown, we believe focal or gross metaplastic changes lead to transformation of tumor cells into the xanthomatous subtype. Authors discuss this interesting a rare histologic variant with discussion of the relevant literature.
 

Keywords: Meningioma, Metaplasia, Radiology


How to cite : Patil N R, Tripathi M, Aulakh S, Banerjee N, Sekar A, Batish A, Ahuja C K, Mohindra S, Xanthomatous meningioma, a rare histological variant: Case report. IP Arch Cytol Histopathol Res 2021;6(4):305-310

Copyright © 2021 by author(s) and IP Arch Cytol Histopathol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)







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