IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...

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Case Report


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117-120


Authors Details

Rajat Kumar*, Khushbu Kumari


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Insulinoma- Rare pancreatic tumor


Case Report

Author Details : Rajat Kumar*, Khushbu Kumari

Volume : 9, Issue : 2, Year : 2024

Article Page : 117-120

https://doi.org/10.18231/j.achr.2024.024



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Abstract

Insulinoma is hormone producing neuroendocrine pancreatic tumor. Insulinoma is a type of functional neuroendocrine tumor characterized by hypersecretion of insulin, causing hypoglycemia. It typically presents as a solitary benign tumor but can be associated with multiple endocrine neoplasia type 1 (MEN1). Patients with insulinoma have hypoglycemic episodes, more characteristically as fasting hypoglycemia.46 yrs. old male having recurrent episode of Syncopal attack, sweating, excessive thrust, and weakness last 3 to 4 yrs. His blood sugar level was always below normal range at time of attack. No H/O diabetes, Hyper tension or any other chronic illness.On detail examination and investigation, we found that his blood sugar level fall 01 hrs. After food intake and blood sugar fasting and post prandial (F=46 mg/dl & PP= 180 mg/dl) is impaired. C Peptide level, serum insulin level is high. MRI shows growth near head of pancreas.Partial pancreatectomy done and sample send for histopathological examination which shows well differentiated pancreatic neuroendocrine tumor with no lymph node involvement and congested spleen.The Whipple triad, named after the American surgeon Allen O. Whipple (1881-1963), is the diagnostic hallmark establishing the existence of a hypoglycemic disorder and has the following 3 features: (1) symptoms, signs, or both consistent with hypoglycemia; (2) low plasma glucose measured at the time of the symptoms and signs; and (3) relief of symptoms and signs when the glucose is raised to a normal level (2, 3). Insulinoma is usually diagnosed by biochemical testing. Surgical resection is the preferred treatment choice.
 

Keywords: Insulinoma, Insulin, Neuroendocrine tumor, Syncopal Attack


How to cite : Kumar R, Kumari K, Insulinoma- Rare pancreatic tumor. IP Arch Cytol Histopathol Res 2024;9(2):117-120

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