IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination more...


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Kaur and Agarwal: To study relation between size of ovary and various histomorphological patterns at SRMSIMS


Introduction

Morphological variety of ovarian tumors presents numerous difficulties. Consciousness of event and recurrence of these examples and cell types in different tumor and tumor like injuries is of fundamental indicative significance. At long last, clinical information, usable discoveries and gross highlights of the injuries may give significant and on occasion definitive analytic clues.1

The principal meeting of the WHO ovarian gathering without FIGO interest was held in St Petersburg in 1965.2 Material was circled among the different members and talked about at a progression of gatherings that occurred somewhere in the range of 1967 and 1971. At last, the arrangement (and chose cases) was explored by a second gathering of pathologists, and the last characterization was received and distributed in 1973 as one of the natural 'blue books' of the International Histological Classification of tumor distributions of that era.3

A critical step toward a histogenesis-based characterization framework was made in 1973 with the distribution of the World Health Organization (WHO) Classification of Ovarian Tumours 4.

This characterization framework was refreshed in 1999 second time and 2003 third time and was affirmed by the International Society of Gynecological Pathologists. 5. Two coding frameworks, the WHO International Classification of Diseases for Oncology and the College of American Pathologists Systematized Nomenclature of Medicine, are normally used to code the histology/morphology of tumours. 6

Table 1

Co-relation of radiological findings with non neoplastic histopathological diagnosis

Histoogical Types

Benign Ovarian Cyst

Complex Ovarian Cyst

Adnexal Mass

Hemorrhagic Cyst Ovary

Bulky Uterus

Total

Non specific oopheritis

03

02

0

0

0

05

Tuberculous

00

01

0

0

0

01

Follicular cyst

05

01

0

01

01

07

Simple serous cyst

20

00

02

00

02

24

Luteal cyst

15

00

01

00

01

16

Hemorrhagic cyst

05

01

00

03

00

09

Endometriosis

03

01

00

00

00

04

Total

51

06

03

04

04

66

Table 2

Correlation of Radiological Findingswith Neoplastic Histopathological Diagnosis

Histoogical types

Adnexal mass

Benign ovarian cyst

Dermoid cyst

Neoplastic ovarian mass

Total

Benign

02

06

06

10

24

Borderline

00

00

00

01

01

Malignant

03

01

01

13

18

Total

05

07

07

24

43

This framework is superior to other past arrangement of characterization as all angle of tumors can be put in a portion of the class. Additionally as it depends on the cell of beginning, so frequency and age related changes could be better understood. 7

Materials and Methods

The present study is based on histomorphological evaluation in 107 cases of Ovarian neoplastic and non-neoplastic lesions received at the department of Pathology of Due importance was paid to record inpatient number, age, parity, family history, menstrual status, clinical history including presenting symptoms and signs, operation done, operative findings, radiological findings. Thorough gross examination was carried out and salient features were noted down.

Gross examination was done carefully examining the outer surface and on-cut surface of ovary, looking for any cyst with its content and type of fluid filled inside, any solid area, papillary projections and growth. Associated tissue piece if received were also carefully examined and grossed. Multiple sections from each specimen were taken to include the representative area for histological examination. Sections were processed by routine paraffin method and blocks were cut at five micron thickness.

Results

Radiologically, of total 66 non neoplastic cases, 51 are reported as benign ovarian cyst, 05 as complex ovarian cyst, 04 as hemorrhagic cyst, 03 as bulky uterus and 02 as adenexal mass. 03 out of 05 cases of non specific oophoritis are reported as benign ovarian cyst, all 01 cases of tuberculosis are reported as complex ovarian cyst. Of 07 follicular cysts, 05 are reported as benign ovarian cyst, 01 as complex ovarian cyst and one each as hemorrhagic cyst and bulky uterus. Of 24 cases diagnosed as simple serous cyst histologically, 20 are reported as benign ovarian cyst, 02 as bulky uterus and 02 as adenexal mass. 04 out of 04 cases of endometriosis are reported as benign ovarian cyst.

Out of 24 benign tumours, 10 are reported as neoplastic ovarian mass, 06 as dermoid cyst, 06 as benign ovarian cyst and 02 as adenexal mass. Of 18 pathologically diagnosed malignant tumours, 13 are reported as neoplastic ovarian mass, 01 as adenexal mass,one each as dermoid cyst and as benign ovarian cyst. 01 out 01 borderline tumours are reported as neoplastic ovarian mass radiologically.

Discussion

Ovarian tumors in the pediatric age bunch are not infrequent,8 the occurrence to be six percent of every single ovarian tumor. Sawai and Sirsat recorded the rate as 11.2% (Sawai MM et al, 1973).9

Of non neoplastic injuries most basic finding in our investigation is basic serous pimple (36%) trailed by luteal growth (25%). R Jha et al10 discovered 30.3% basic serous growth and 22.7% luteal sore. In their investigation vague oophoritis was found in 9.0% of cases while we found in 7.5% of the cases. In R Jha.et al study, 78.9% of serous tumors were amiable and 21.1% were dangerous, comparably 77.8% of mucinous tumors were kind neoplasms while 22.2% were malignancies similar to introduce study, in serous 93% were favorable and 7% were harmful. In Nital.et al11 concentrate the same of our examination among mucinous tumors 12(80%) were generous, 1(6.7%) fringe and 2(13.3%) harmful. In present investigation, out of 12 mucinous tumors, 10 (83.3%) were favorable, 1(8.3%) fringe and 1(8.3%) was dangerous.

Ovarian tumors are the most engaging neoplasms regarding root, clinical introduction and harmful potentiality.12 Accordingly, it excited interest and challenges to pathologists and clinicians in regards to their unusual substance and histogenesis. So a definite investigation of morphological examples of ovarian tumors is required for arranging the treatment methodology and to survey the anticipation.

Conclusion

Viable therapeutic administration of ovarian dangerous tumors keeps on being a test to the oncologist. A precise histopathological determination joined with clinical organizing will help in delivering expeditious and fitting treatment to the patient. The ovary is a successive site for essential malignancy. Because of various cell types and its unpredictable design, essential ovarian neoplasms are of different histological types.

Source of Funding

No financial support was received for the work within this manuscript.

Conflict of Interest

The authors declare that they have no conflict of interest.

References

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2 

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3 

J Curtin Management of the Adnexal MassGynecol Oncol 1994553S42610.1006/gyno.1994.1340

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M M Sawai M V Sirsat Ovarian neoplasm in children and adolescentsIndian J Cancer19731030211

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V Tejesweni G Vahini S Reddy P Premalatha Study of morphological patterns of ovarian neoplasmsIOSR J Dent Med Sci (IOSR-JDMS)2013106116



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Article type

Original Article


Article page

81-83


Authors Details

Dupinder Kaur, Pooja Agarwal


Article History

Received : 12-01-2021

Accepted : 15-03-2021

Available online : 29-05-2021


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